Catalyst: Music on the Braindownload video: mp. Dr Maggie Haertsch. Music predates language. There's something very primal about music.

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NARRATIONIf you had to make a playlist of your life, what would be on it? ABBA: Mamma Mia. NARRATIONThe music of your childhood? INXS: Need You Tonight. NARRATIONThe backbeats of your teens.

The music that always makes you cry. RIGHTEOUS BROTHERS: Unchained Melody. NARRATIONOr fills you with joy. THE BEACH BOYS: God Only Knows. NARRATIONAnd if, toward the end of your life, your mind and memories were fading away, would this soundtrack help bring them back? In this episode, we're going to show you a remarkable program that is bringing personalised music to people with dementia..

Mary Clark. Everybody, up. NARRATION. waking up their inner lives. Erin Sharp. I was stunned at the conversation that she had post the music. NARRATIONAnd even helping people with advanced Parkinson's to unfreeze and move. And along the way, we'll look more deeply at the power of music in all our lives. Why is it so emotional, so memorable and so powerful that even when much of the brain is gone, music can bring it alive? This is Leigh Place Aged Care Home, and this is John.

He used to be in the Navy, but he doesn't remember much of that now. Or much of anything. But next door, a prescription is being prepared they hope will peel back the dementia fog. Amy. So, we've got John's playlist.. NARRATIONOnly it's not a pill, it's an i. Pod with a tailor- made playlist just for him.

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Amy. Can I just pop these headphones on you? John. Yeah. NARRATIONThe residents are about to hear some of their favourite music, and for some, it'll be the first time they've heard it in years. Amy. Are you ready? It's a long way to Tipperary. It's a long way to go.. NARRATIONThe change is startling, instant.

John. To the sweetest girl I know.. NARRATIONThis facility is one of the first in Australia to take on a new program of personalised music called Music & Memory, and for John, it's clearly taking him back. John. You know what they call that song? Amy. Which song? This one just now? John. It's A Long Way To Tickle Mary.

Amy. To Tickle Mary. What relation am I to you? Mary Clark. Well, I was just trying to work it out. I'm your son. Mary Clark. Oh, he's my son. No, that's just..

Everybody, up. I love running. Graham Hooper. What we find is people with dementia, they start to withdraw into themselves.

So, what we're finding with the Music & Memory program is the music allows them to reconnect with their family member. Graham Hooper. It was good to hear you sing. Graham Hooper. That ability to reconnect husbands with wives, sons and daughter with their mum or dad is just a fantastic thing.

It's very, very powerful. Mary Clark. I'm having a real happy night. It's very happy, yeah. Music predates language. There's something very primal about music. Now, if we're able to access our music when we're growing up through the generations, why is that we can't get music when we need it most?

And now we absolutely need to make sure that music, in this such a simple way, is able to be accessible in healthcare environments. NARRATIONAnd the science is suggesting there's more to it than just the emotional feel- good factor.

In its best study benefit, researchers from Stanford University, California, have shown prescribed music can reduce one of the more distressing aspects of Alzheimer's - agitation - where confused, stressed individuals act out or shout. Man. Goodbye. NARRATIONIt may even reduce the need for antipsychotics, often prescribed for agitation. Graham Hooper. So, for example, John - he has limited mobility, he shouldn't really be getting out of his chair by himself. Sometimes, if he's agitated, he'll be trying up and down, up and down out of the chair. So instead of the staff having to constantly come over to John, reassure him, ask him to sit down again, we can put the headphones on.

He's relaxed, he's calm, he's at peace. It's fantastic. Better than drugs. NARRATIONSo the right playlist can penetrate even the thickest fog of dementia, which begs the question - how? John(Hums)NARRATIONThe fact is music does something to our brains no other stimulus can do.

And here, at the Music, Sound and Performance Lab, we're going to show you. Professor Mark Williams. The main thing is to take off all the metal. We need to get all the metal off your body.

NARRATIONMy examiners are Professor Mark Williams and Professor Bill Thompson, a world expert on music and emotions, as well as a composer himself. Professor Bill Thompson. So, you've chosen a couple of pieces of music to listen to. Do you want to say anything about those? Dr Jonica Newby. I've chosen a piece from The Mission that I really love and another piece by a group called Train.

NARRATIONAs far as we're aware, this is the first time scientists have ever tried to show real- time brain responses to favourite music in a magnetoencephalography machine. So we're all a bit nervous to see if it works.

ENNIO MORRICONE: The Mission Theme Music. NARRATIONAs the music starts, my mind is flooded with memories. A Tuscan hillside, an old church, a moment shared with a loved one. And with it comes overwhelming emotion.

TRAIN: Hey, Soul Sister. NARRATIONNow, this piece is completely different. It fills me with joy. I'm struggling to stay still. Woman. Pretty much she's blinking a lot during the pauses.

NARRATIONMany repeats later, I'm finally released. Professor Bill Thompson. Congratulations, you did it. How was it? Dr Jonica Newby. Bit shattered after that, actually. Professor Mark Williams. So, here are the results, which have been really exciting, 'cause we've got lots of activation to each of the pieces.

We've got these emotional areas here in the front of the brain. The Mission piece is much more involved in the emotion areas.

We've also got a lot of activation here on the temporal lobe, which is more for memories of emotions, and the Amygdala, which is involved in physiological responses to emotion. Dr Jonica Newby. Wow. Professor Mark Williams. But also a lot of motor areas. So these are the areas involved in moving your hands. And the interesting thing is that between the two different pieces, we got very different activations - one much more involved in emotions and one much more involved in actually moving, so the motor areas. Dr Jonica Newby. Wow, that's fantastic, 'cause, I mean, I could feel that.

I'm amazed that you can actually see that so clearly on the brain. Professor Mark Williams. Yeah, and it's very strong. NARRATIONThis is what we were hoping to see.

It shows what's unique about music in the brain. It's embedded nearly everywhere, from emotional centres to memory centres to movement. And that helps explain why, even when much of the brain is gone, music can wake it up. Professor Bill Thompson. It's like a superstimulus. So much of your brain is involved that I think that that means that there is more opportunity for the effects of music to be preserved in the face of damage. NARRATIONSo that's why music is so powerful.

But I want to know, why is it so emotional? Download Naruto Season Subtitle Indonesia Moon on this page. And why does some music conjure joy and others make us cry? Professor Bill Thompson.

The piece from The Mission is a really powerful piece, and I think there's a lot going on there. I think the oboe has a kind of voice- like quality, a crying voice, a sad and melancholy vocalisation. And you have empathy for that kind of yearning sound of the melody. The other aspect of The Mission is it's quite a slow tempo, so it's got a lot of the qualities that would generate a kind of sad or calm feeling. ENNIO MORRICONE: The Mission Theme Music. NARRATIONSlow music calms our physiology down. TRAIN: Hey, Soul Sister.

NARRATIONFaster music invites it to speed up, which is why so many of us use it for exercise. Professor Bill Thompson. In the music, Train, it's much faster. The motor cortex is engaged heavily. You might be tapping along to the music, so you're literally moving. Your breathing is faster, your heart rate increases and, thereby, increase your arousal levels and your energy.